Eosinophilic folliculitis in association with chronic lymphocytic leukemia: A clinicopathologic series

BMT: bone marrow transplantation CLL: chronic lymphocytic leukemia EF: eosinophilic folliculitis NHL: non-Hodgkin lymphoma SCT: stem cell transplantation WBC: white blood cell INTRODUCTION Well-recognized variants of eosinophilic folliculitis (EF), also known as eosinophilic pustular folliculitis, include Ofuji disease, infantile EF, and HIV-associated EF, which is considered a defining illness of AIDS. A fourth less commonly recognized subtype of EF is that associated with hematologic malignancy, in particular leukemia and non-Hodgkin lymphoma (NHL). EF in HIV-negative individuals and associated with hematologic malignancy was first reported in 1993. ThisvariantofEFmaybeunderrecognizedanddifficult to diagnose given the clinical scenario, morphology, and variable histologic findings, detailed in a series of 3 patients with EF in association with chronic lymphocytic leukemia (CLL) presented herein.